HCID 86761463, compound → HCID 86761461, compound

HRID 657476Notes

Reaction equation

HRID 657476 reaction equation
[Na:1].N1C(N)=C2C(N(C3(OC[C@H](OCP(O)(O)=O)[C@H]3O)O)C=N2)=NC=1.[N:25]1([C:34]2([O:52][CH2:51][C@H:38]([O:39][CH2:40][P:41]([O:47]C(C)C)([O:43]C(C)C)=[O:42])[C@H:36]2[OH:37])[OH:35])[CH:33]=[C:31]([CH3:32])[C:29](=[O:30])[NH:28][C:26]1=[O:27]>>[Na:1].[N:25]1([C:34]2([O:52][CH2:51][C@H:38]([O:39][CH2:40][P:41]([OH:43])([OH:47])=[O:42])[C@H:36]2[OH:37])[OH:35])[CH:33]=[C:31]([CH3:32])[C:29](=[O:30])[NH:28][C:26]1=[O:27]

Participants

3

Reactant 2

HCID 86761463HCID 86761463, compoundHCID 86761465HCID 86761465, compound

Product 1

HCID 86761461HCID 86761461, compoundYield 42%

Procedure

This compound was prepared as described for 3a, using 16 (220 mg, 0.58 mmol) as starting material. Compound 3b (90 mg, 0.24 mmol) was obtained as a colorless solid in 42% yield, which was characterized as follows:

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-c72c0e861f7543d5bd34e275df7c4fa5
Source dataset
uspto-grants-2011_12
Patent number
US08076310B2

Reaction notes

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