HCID 86761456, compound → HCID 86761468, compound

HRID 657478Notes

Reaction equation

HRID 657478 reaction equation
[Na:1].N1C(N)=C2C(N(C3(OC[C@H](OCP(O)(O)=O)[C@H]3O)O)C=N2)=NC=1.[N:25]1([C:33]2([O:51][CH2:50][C@H:37]([O:38][CH2:39][P:40]([O:46]C(C)C)([O:42]C(C)C)=[O:41])[C@H:35]2[OH:36])[OH:34])[CH:32]=[CH:31][C:29]([NH2:30])=[N:28][C:26]1=[O:27]>>[Na:1].[N:25]1([C:33]2([O:51][CH2:50][C@H:37]([O:38][CH2:39][P:40]([OH:42])([OH:46])=[O:41])[C@H:35]2[OH:36])[OH:34])[CH:32]=[CH:31][C:29]([NH2:30])=[N:28][C:26]1=[O:27]

Participants

3

Reactant 2

HCID 86761456HCID 86761456, compoundHCID 86761463HCID 86761463, compound

Product 1

HCID 86761468HCID 86761468, compoundYield 43%

Procedure

This compound was prepared as described for 3a, using 18 (150 mg, 0.38 mmol) as a starting material. Compound 3d (58 mg, 0.16 mmol) was obtained as a colorless solid, in 43% yield, which was characterized as follows:

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-97921f5d87d3414db1a0d41b0911f7d0
Source dataset
uspto-grants-2011_12
Patent number
US08076310B2

Reaction notes

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