HCID 86761463, compound → HCID 178507174, compound

HRID 657479Notes

Reaction equation

HRID 657479 reaction equation
[Na:1].[N:2]1[C:10]([NH2:11])=[C:9]2[C:5]([N:6](C3(OC[C@H](OCP(O)(O)=O)[C@H]3O)O)[CH:7]=[N:8]2)=[N:4][CH:3]=1.N1C(N)=C2C(N([C:35]3([O:52][CH2:51][C@H:38]([O:39][CH2:40][P:41]([O:47]C(C)C)([O:43]C(C)C)=[O:42])[CH2:37]3)[OH:36])C=N2)=NC=1>>[Na:1].[N:2]1([C:35]2([O:52][CH2:51][C@H:38]([O:39][CH2:40][P:41]([OH:47])([OH:43])=[O:42])[CH2:37]2)[OH:36])[C:10]([NH2:11])=[C:9]2[C:5](=[N:6][CH:7]=[N:8]2)[N:4]=[CH:3]1

Participants

3

Reactant 2

HCID 86761463HCID 86761463, compoundHCID 86761472HCID 86761472, compound

Product 1

HCID 178507174HCID 178507174, compoundYield 43%

Procedure

This compound was prepared as described for 3a, using 19 (70 mg, 0.23 mmol) as a starting material. Compound 3e (38 mg, 0.11 mmol) was obtained as a colorless solid, in 43% yield, which was characterized as follows:

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-d3e619f048a94f25b52ecdf4069fa555
Source dataset
uspto-grants-2011_12
Patent number
US08076310B2

Reaction notes

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