Gamma-Aminobutyric Acid → HCID 23150258, compound

HRID 657625Notes

Reaction equation

HRID 657625 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[NH2:12][CH2:13][CH2:14][CH2:15][C:16](O)=O>>[Cl:1][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:16]2[CH2:15][CH2:14][CH2:13][N:12]=2)=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 119Gamma-Aminobutyric AcidHCID 76917(3-Chloropropoxy)benzene

Product 1

HCID 23150258HCID 23150258, compoundYield 9.3%

Procedure

Following the procedure described in example 1§A, but starting from O-(3-chloropropyl)phenol (3.41 g), 4-aminobutanoic acid (2.06 g) and polyphosphoric acid (36 g) gives 0.44 g of 2-[4-(3-chloropropoxy)phenyl]-4,5-dihydro-3H-pyrrole.

Sources & evidence

ORD record
ord-91f6f4e8c4224b6ba1f31895feb50dcf
Source dataset
uspto-grants-2011_12
Patent number
US08076329B2

Reaction notes

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