HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 1-[3-(4-Iodophenoxy)propyl]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(3-Chloropropoxy)-4-iodobenzene | HCID 15895520 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-[3-(4-Iodophenoxy)propyl]piperidine | HCID 2304773 | 99.9% |
Reaction Steps
Following the procedure described in example 1§E, but starting from 1-(3-chloropropoxy)-4-iodobenzene (3 g), potassium carbonate (4.15 g) and piperidine (1.7 g) in N,N-dimethylformamide (30 mL) affords 3.49 g of 1-[3-(4-iodophenoxy)propyl]piperidine used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076329B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-41d383dbdb9440319f43c1491c845a91 |
| Source note | uspto-grants-2011_12 |