反应详情

2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine (4.25 g) and 1,1-bis(methylthio)-2-nitroethene (3.3 g) were refluxed in acetonitrile (50 ml) for 14 hr. Solvent was removed and the residue dissolved in 36% methanolic methylamine (50 ml) and the solution refluxed for 8 hr. Solvents were removed and the residue in methanol treated with charcoal. Filtration and evaporation of the solvent gave the title compound as Example 15 (5.0 g).

1. customSolvent was removed
2. dissolutionthe residue dissolved in 36% methanolic methylamine (50 ml)
3. temperaturethe solution refluxed for 8 hr
4. customSolvents were removed
5. additionthe residue in methanol treated with charcoal
6. filtrationFiltration and evaporation of the solvent