HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → 4-(4-Methoxyphenyl)-2-methylpyridine 1-oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 4-(4-Methoxyphenyl)-2-methylpyridine | HCID 23371780 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-(4-Methoxyphenyl)-2-methylpyridine 1-oxide | HCID 57672027 | 94.8% |
Reaction Steps
A mixture of 4-(4-methoxyphenyl)-2-methylpyridine (375 mg) and metachloroperbenzoic acid (70%, 695 mg) in chloroform is stirred at room temperature for two hours. Concentration and purification over silica gel (eluent dichloromethane/methanol from 100/0 to 90/10) affords 384 mg of 4-(4-methoxyphenyl)-2-methylpyridine 1-oxide as an orange oil used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076329B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-855eb5495fd343ae88346529c7e01f65 |
| Source note | uspto-grants-2011_12 |