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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 657674Generated: October 31, 2026

HCID 68908311, compound → HCID 178479702, compound

https://huagongshe.com/reaction/657674

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68908311HCID 68908311—
ReactantHCID 131729324HCID 131729324—
ProductHCID 178479702HCID 178479702—

Reaction Steps

A Reduction of 1-{3-[4-(4-oxocyclohexyl)phenoxy]propyl}pyrrolidine (456 mg) as described for (3S)-1-{3-[4-(4-hydroxycyclohexyl)phenoxy]propyl}-3-methylpiperidine, hydrochloride affords 120 mg of 1-{3-[trans-4-(4-hydroxycyclo-hexyl)phenoxy]propyl}pyrrolidine, hydrochloride as a white solid melting at 225° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076329B2
Source datasetuspto-grants-2011_12
ORD IDord-e09eec7ac8544ac5b3c3f42c7c207926
Source noteuspto-grants-2011_12