HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanone → HCID 6461364, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | 3-Hydrazinobenzoic acid | HCID 2736521 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 6461364 | HCID 6461364 | — |
Reaction Steps
A mixture of 2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid and 2,3,4,9-tetrahydro-1H-carbazole-5-carboxylic acid was obtained by allowing cyclohexanone and 3-hydrazinobenzoic acid to undergo the reaction under heating in acetic acid. By separating and purifying this mixture by a silica gel column chromatography, 2,3,4,9-tetrahydro-1H-carbazole-5-carboxylic acid [Reference Example 16a: FAB: 216 (M+H)+] and 2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid [Reference Example 16b: FAB: 216 (M+H)+] were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076348B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-8c99837f2a1e486dbdacdd692ed106e7 |
| Source note | uspto-grants-2011_12 |