HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 5311907, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 6461364 | HCID 6461364 | — |
| Reactant | 2,3,4,9-tetrahydro-1H-carbazole-5-carboxylic acid | HCID 6463966 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 5311907 | HCID 5311907 | — |
Reaction Steps
By adding thionyl chloride to a methanol solution of a mixture of 2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid and 2,3,4,9-tetrahydro-1H-carbazole-5-carboxylic acid at −10° C., followed by the reaction under heating and subsequent separation and purification by a column chromatography, methyl 2,3,4,9-tetrahydro-1H-carbazole-7-carboxylate [Reference Example 17a: ESI: 2230 (M+H)+] and methyl 2,3,4,9-tetrahydro-1H-carbazole-5-carboxylate [Reference Example 17b: ESI: 230 (M+H)+] were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076348B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-4b078ee7227c4465a42bcce0632a569b |
| Source note | uspto-grants-2011_12 |