HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Pyridin-4-yl)boronic acid → HCID 67438967, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Pyridin-4-yl)boronic acid | HCID 2734379 | — |
| Reactant | 4-bromoisophthalic acid diethyl ester | HCID 11524187 | — |
| Reactant | HCID 67425064 | HCID 67425064 | — |
| Reactant | HCID 178418821 | HCID 178418821 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67438967 | HCID 67438967 | — |
Reaction Steps
9-Oxo-9H-indeno[2,1-c]pyridine-7-carboxylic acid was obtained by allowing 4-pyridin-4-ylphthalic acid [FAB: 244 (M+H)+] which had been synthesized by carrying out the same operations of Reference Examples 27 and 28 using 4-bromoisophthalic acid diethyl ester and 4-pyridine boronic acid to undergo the reaction with lithium 2,2,6,6-tetramethylpiperidide at 0° C. in THF. By carrying out reaction of this compound by the same method of Reference Example 30, ethyl 9-oxo-9H-indeno[2,1-c]pyridine-7-carboxylate was obtained. FAB: 254 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076348B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-bfe3bae7c549487b9ba1fe6329e23ce0 |
| Source note | uspto-grants-2011_12 |