HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-azido-2-(6-methoxypyridin-3-yl)ethanol → (S)-2-Amino-2-(6-methoxypyridin-3-yl)ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-azido-2-(6-methoxypyridin-3-yl)ethanol | HCID 58103593 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (S)-2-Amino-2-(6-methoxypyridin-3-yl)ethanol | HCID 55278315 | 100.8% |
Reaction Steps
A mixture of (S)-2-azido-2-(6-methoxypyridin-3-yl)ethanol (0.90 g, 4.6 mmol), EtOAc (50 mL), and 10% Pd—C (100 mg) was stirred under H2 (1 atm) for 1 h. The catalyst was filtered off and the filtrate was concentrated in vacuo to yield a thick oil (0.78 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076345B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-fbaccf3ec7ef42548c36004c0a991920 |
| Source note | uspto-grants-2011_12 |