HCID 86624407, compound → HCID 68420239, compound

Participants

Reaction Steps

A mixture of (S)-5-(1-azido-2-(tert-butyldimethylsilyloxy)ethyl)-2-methoxypyrimidine (11.7 g, 37.7 mmol) in ethyl acetate (300 mL), and 10% Pd—C (70 mg) was stirred under H2 (1 atm) overnight. The catalyst was filtered off and the filtrate was concentrated to yield a light oil. The residue was purified by silica gel chromatography (0-50% MeOH/EtOAc) to afford a colorless oil.

Provenance & Evidence