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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 657766Generated: November 3, 2026

Hydrochloric Acid → HCID 58103573, compound

https://huagongshe.com/reaction/657766

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 66872457HCID 66872457—
ProductHCID 58103573HCID 58103573—

Reaction Steps

(R)—N—((R)-Cyclopropyl(6-(trifluoromethyl)pyridin-3-yl)methyl)-2-methylpropane-2-sulfinamide (0.245 g, 0.000765 mol), ethanol (2.7 g, 0.059 mol), and 4.0 M of hydrogen chloride in dioxane (2.7 mL, 0.011 mol) were combined and stirred overnight. Reaction was concentrated to down to oil and then redissolved and washed with ethanol for 3 times, and concentrated. The residue was dried on the high vacuum overnight to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076345B2
Source datasetuspto-grants-2011_12
ORD IDord-c4d40bef71e748109954805f1c147d3a
Source noteuspto-grants-2011_12