Butylamine → N-Butyl-11-(butylimino)-1-ethyl-1,5,6,11-tetrahydrobenzo-[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]pyridin-4-amine

HRID 65780Notes

Reaction equation

HRID 65780 reaction equation
Cl[C:2]1[C:7]2[CH:8]=[N:9][N:10]([CH2:11][CH3:12])[C:6]=2[N:5]=[C:4]2[C:13](=O)[C:14]3[CH:21]=[CH:20][CH:19]=[CH:18][C:15]=3[CH2:16][CH2:17][C:3]=12.[CH2:23]([NH2:27])[CH2:24][CH2:25][CH3:26]>CCOCC>[CH2:23]([NH:27][C:2]1[C:7]2[CH:8]=[N:9][N:10]([CH2:11][CH3:12])[C:6]=2[N:5]=[C:4]2[C:13](=[N:5][CH2:4][CH2:3][CH2:2][CH3:7])[C:14]3[CH:21]=[CH:20][CH:19]=[CH:18][C:15]=3[CH2:16][CH2:17][C:3]=12)[CH2:24][CH2:25][CH3:26]

Participants

4

Reactant 2

HCID 8007ButylamineHCID 203820734-chloro-1-ethyl-5,6-dihydrobenzo[5,6]-cyclohepta[1,2-b]pyrazolo[4,3-e]pyridin-11(1H)-one

Product 1

HCID 22757739N-Butyl-11-(butylimino)-1-ethyl-1,5,6,11-tetrahydrobenzo-[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]pyridin-4-amine

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

10.8 g. of 4-chloro-1-ethyl-5,6-dihydrobenzo[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]pyridin-11(1H)-one (0.035 mol.) and 100 ml. of butylamine are reacted in an autoclave by the procedure of Example 5, yield: 9.8 g. (70%); m.p. 124°-125° (ether; refrigerator).

Sources & evidence

ORD record
ord-c76621eeab30483ebb8cdb44804f2ebd
Source dataset
uspto-grants-1978_12
Patent number
US04128717

Reaction notes

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