2-Hydrazinopyridine → 3-TERT-BUTYL-1-(PYRIDIN-2-YL)-1H-PYRAZOL-5-AMINE

HRID 657844Notes

Reaction equation

HRID 657844 reaction equation
[CH3:1][C:2]([CH3:9])([CH3:8])[C:3](=O)[CH2:4][C:5]#[N:6].[NH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=1)[NH2:11]>>[C:2]([C:3]1[CH:4]=[C:5]([NH2:6])[N:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)[N:11]=1)([CH3:9])([CH3:8])[CH3:1]

Participants

3

Reactant 2

HCID 786452-HydrazinopyridineHCID 108871Pentanenitrile, 4,4-dimethyl-3-oxo-

Product 1

HCID 433813303-TERT-BUTYL-1-(PYRIDIN-2-YL)-1H-PYRAZOL-5-AMINEYield 99%

Procedure

The title compound was prepared from 4,4-dimethyl-3-oxopentane nitrile and 2-hydrazinopyridine, using the same method as that described for preparation 7, as a solid in 99% yield.

Workup

  1. customthat described for preparation 7, as a solid in 99% yield

Sources & evidence

ORD record
ord-602efdbb90324ac78b178b07e68ae827
Source dataset
uspto-grants-2011_12
Patent number
US08076356B2

Reaction notes

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