HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → N-[3-mercapto-2-(methoxycarbonylmethyl)propanoyl]-L-cysteine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | N-[3-(acetylthio)-2-(methoxycarbonylmethyl)propanoyl]-S-(N-ethylcarbamoyl)-L-cysteine | HCID 57011645 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-[3-mercapto-2-(methoxycarbonylmethyl)propanoyl]-L-cysteine | HCID 54045483 | — |
Reaction Steps
To a solution of N-[3-(acetylthio)-2-(methoxycarbonylmethyl)propanoyl]-S-(N-ethylcarbamoyl)-L-cysteine (1.9 g.) in methanol (10 ml.), sodium methoxide (0.84 g.) is added. After 30 minutes, the solution is diluted with 0.1 N hydrochloric acid and extracted with ethyl acetate. The organic layer is dried and concentrated to dryness in vacuo to yield N-[3-mercapto-2-(methoxycarbonylmethyl)propanoyl]-L-cysteine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04128721 |
| Source dataset | uspto-grants-1978_12 |
| ORD ID | ord-eec97ba1093549458060915332856a35 |
| Source note | uspto-grants-1978_12 |