HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxygen → 3'-Chloro-5'-methoxyacetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxygen | HCID 977 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Ozone | HCID 24823 | — |
| Reactant | Methanamine, N-methoxy-, hydrochloride (1:1) | HCID 81138 | — |
| Reactant | 3-Chloro-5-methoxybenzoic acid | HCID 12909341 | — |
| Reactant | HCID 178418573 | HCID 178418573 | — |
| Product | 3'-Chloro-5'-methoxyacetophenone | HCID 13493854 | — |
Reaction Steps
3-Chloro-5-methoxybenzoic acid (3 g) was reacted analogously to O3.043/O2.043 with thionyl chloride (23.3 ml) and N,O-dimethylhydroxylamine hydrochloride (1.57 g) and methylmagnesium bromide (8.91 ml). 2.42 g were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076336B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-33c0a7ada5f944c3be2b22fee03974b0 |
| Source note | uspto-grants-2011_12 |