Oxygen → HCID 58045772, compound

HRID 657978Notes

Reaction equation

HRID 657978 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([C:12](=[O:14])[CH3:13])[CH:8]=[C:9]([OH:11])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].Br[CH2:16][CH2:17][CH2:18][F:19].O=O>>[C:1]([C:5]1[CH:6]=[C:7]([C:12](=[O:14])[CH3:13])[CH:8]=[C:9]([O:11][CH2:16][CH2:17][CH2:18][F:19])[CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 3

HCID 977OxygenHCID 67699Propane, 1-bromo-3-fluoro-HCID 58045815HCID 58045815, compound

Product 1

HCID 58045772HCID 58045772, compound

Procedure

1-(3-tert-Butyl-5-hydroxyphenyl)ethanone (O3.106; 500 mg) was reacted with 1-bromo-3-fluoropropane (239 μl) and worked up analogously to O2.105. 630 mg of the title compound were obtained. LC-MS rt: 1.16 min [M+H]+: 253.2 (met. b)

Sources & evidence

ORD record
ord-0acb13a8a33a4bcab07ff9d8fdc56b93
Source dataset
uspto-grants-2011_12
Patent number
US08076336B2

Reaction notes

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