3-Bromo-2,2-dimethylpropyl acetate → Methyl 3-(3-acetoxy-2,2-dimethylpropoxy)-5-tert-butylbenzoate

HRID 658009Notes

Reaction equation

HRID 658009 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([CH:12]=[C:13]([OH:15])[CH:14]=1)[C:8]([O:10][CH3:11])=[O:9])([CH3:4])([CH3:3])[CH3:2].[C:16]([O:19][CH2:20][C:21]([CH3:25])([CH3:24])[CH2:22]Br)(=[O:18])[CH3:17]>>[C:16]([O:19][CH2:20][C:21]([CH3:25])([CH3:24])[CH2:22][O:15][C:13]1[CH:12]=[C:7]([CH:6]=[C:5]([C:1]([CH3:4])([CH3:2])[CH3:3])[CH:14]=1)[C:8]([O:10][CH3:11])=[O:9])(=[O:18])[CH3:17]

Participants

3

Reactant 2

HCID 133577153-Bromo-2,2-dimethylpropyl acetateHCID 53399216Methyl 3-tert-butyl-5-hydroxybenzoate

Product 1

HCID 58046018Methyl 3-(3-acetoxy-2,2-dimethylpropoxy)-5-tert-butylbenzoate

Procedure

Methyl 3-tert-butyl-5-hydroxybenzoate (O6.043; 1.79 g) was reacted with 3-bromo-2,2-dimethylpropyl acetate, worked up and purified analogously to 02.85. 1.01 g of the title compound were obtained.

Workup

  1. custompurified analogously to 02.85

Sources & evidence

ORD record
ord-606cf111730846a5b3ccc04ad69faadd
Source dataset
uspto-grants-2011_12
Patent number
US08076336B2

Reaction notes

Loading…