HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Thioglycolate → 6-Methoxy-benzo[B]thiophene-2-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Thioglycolate | HCID 16907 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-Fluoro-4-methoxybenzaldehyde | HCID 2734873 | — |
| Product | 6-Methoxy-benzo[B]thiophene-2-carboxylic acid methyl ester | HCID 53486111 | — |
Reaction Steps
Using 2.5 g (16.2 mmol) of 2-fluoro-4-methoxybenzaldehyde, 0.97 g (24.3 mmol) of sodium hydride (60% pure) and 1.89 g (17.8 mmol) of methyl mercaptoacetate, 3.05 g (84.7% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076355B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-3affe92ddbaa4321a214bbe9ae83ec58 |
| Source note | uspto-grants-2011_12 |