HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Thioglycolate → Methyl 7-nitrobenzo[b]thiophene-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Thioglycolate | HCID 16907 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-Chloro-3-nitrobenzaldehyde | HCID 12667713 | — |
| Product | Methyl 7-nitrobenzo[b]thiophene-2-carboxylate | HCID 57722418 | — |
Reaction Steps
Using 3.04 g (16.4 mmol) of 2-chloro-3-nitrobenzaldehyde, 0.98 g (24.6 mmol) of sodium hydride (60% pure) and 2.09 g (19.7 mmol) of methyl mercaptoacetate, 3.68 g (85% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076355B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-665d0357313742e4b70d9bef1e86d8e2 |
| Source note | uspto-grants-2011_12 |