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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 658313Generated: October 29, 2026

[1,1'-Biphenyl]-4-ol, 4'-(1,1-dimethylethyl)- → racemic 3-{4-[1-(4'-tert-Butyl-biphenyl-4-yloxymethyl)-heptyl]-benzoylamino}-propionic acid

https://huagongshe.com/reaction/658313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[1,1'-Biphenyl]-4-ol, 4'-(1,1-dimethylethyl)-HCID 88262—
Reactant3-[4-(1-Hydroxymethyl-heptyl)-benzoylamino]-propionic acid methyl esterHCID 67485569—
Productracemic 3-{4-[1-(4'-tert-Butyl-biphenyl-4-yloxymethyl)-heptyl]-benzoylamino}-propionic acidHCID 24765137—

Reaction Steps

The title compound is prepared by essentially following the procedures as described in Example 8, using 4′-tert-butyl-biphenyl-4-ol and 3-[4-(1-hydroxymethyl-heptyl)-benzoylamino]-propionic acid methyl ester as starting materials. MS (ES): 528.3 [M+H]−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076374B2
Source datasetuspto-grants-2011_12
ORD IDord-5e000b2118594750957675187120e811
Source noteuspto-grants-2011_12