4-tert-Butylphenylboronic acid → HCID 24765242, compound

HRID 658317Notes

Reaction equation

HRID 658317 reaction equation
C([O:3][C:4](=[O:31])[CH2:5][CH2:6][NH:7][C:8](=[O:30])[C:9]1[CH:14]=[CH:13][C:12]([CH:15]([CH2:19][O:20][C:21]2[CH:26]=[C:25]([CH3:27])[C:24](Br)=[C:23]([CH3:29])[CH:22]=2)[CH:16]([CH3:18])[CH3:17])=[CH:11][CH:10]=1)C.[C:32]([C:36]1[CH:41]=[CH:40][C:39](B(O)O)=[CH:38][CH:37]=1)([CH3:35])([CH3:34])[CH3:33]>>[C:32]([C:36]1[CH:41]=[CH:40][C:39]([C:24]2[C:23]([CH3:29])=[CH:22][C:21]([O:20][CH2:19][CH:15]([C:12]3[CH:11]=[CH:10][C:9]([C:8]([NH:7][CH2:6][CH2:5][C:4]([OH:31])=[O:3])=[O:30])=[CH:14][CH:13]=3)[CH:16]([CH3:18])[CH3:17])=[CH:26][C:25]=2[CH3:27])=[CH:38][CH:37]=1)([CH3:35])([CH3:34])[CH3:33]

Participants

3

Reactant 2

HCID 27343204-tert-Butylphenylboronic acidHCID 67485984HCID 67485984, compound

Product 1

HCID 24765242HCID 24765242, compound

Procedure

The title compound is prepared by essentially following the procedures as described in Example 21, using 3-{4-[1-(4-bromo-3,5-dimethyl-phenoxymethyl)-2-methyl-propyl]-benzoylamino}-propionic acid ethyl ester and 4-tert-butyl phenyl boronic acid as starting materials. MS (ES): 514.2 [M+H]−.

Sources & evidence

ORD record
ord-b18fa128b51c4c8d9ee17374dc64d9c4
Source dataset
uspto-grants-2011_12
Patent number
US08076374B2

Reaction notes

Loading…