HCID 20231697, compound → HCID 57193657, compound

HRID 658332Notes

Reaction equation

HRID 658332 reaction equation
[C:1]([CH2:3][CH2:4][N:5]([CH2:21][CH2:22][C:23]#[N:24])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][N:12]([CH2:17][CH2:18][C:19]#[N:20])[CH2:13][CH2:14][C:15]#[N:16])#[N:2].[H][H]>O1CCOCC1>[NH2:16][CH2:15][CH2:14][CH2:13][N:12]([CH2:17][CH2:18][CH2:19][NH2:20])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][N:5]([CH2:4][CH2:3][CH2:1][NH2:2])[CH2:21][CH2:22][CH2:23][NH2:24]

Participants

4

Reactant 2

HCID 20231697HCID 20231697, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 57193657HCID 57193657, compoundYield 88.5%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

16.42 g of N,N,N′,N′-tetrakis(2-cyanoethyl)-1,6-hexanediamine, 1.64 g of Raney Co and 90 mL of 1,4-dioxane were charged in an autoclave and a hydrogenation reaction was carried out at an initial hydrogen pressure of 9.0 MPa at 180° C. for 2.5 hours. After the catalyst was removed by filtration, the obtained filtrate was concentrated to dryness to give 15.24 g of the title compound.

Workup

  1. customa hydrogenation reaction
  2. customAfter the catalyst was removed by filtration
  3. concentrationthe obtained filtrate was concentrated to dryness

Sources & evidence

ORD record
ord-0f3b2893ce2e4065aafde6f64b8acbde
Source dataset
uspto-grants-2011_12
Patent number
US08076478B2

Reaction notes

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