HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-3-fluorophenol → 4-Amino-3-(methylsulfanyl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-3-fluorophenol | HCID 2735919 | — |
| Reactant | 3-(Methylthio)-4-nitrophenol | HCID 44185702 | — |
| Product | 4-Amino-3-(methylsulfanyl)phenol | HCID 19048349 | 81.3% |
Reaction Steps
This compound was prepared from 3-(Methylsulfanyl)4-nitrophenol (3.2 g, 17.3 mmol) in the manner described for 4-amino-3-fluorophenol, affording 2.18 g (81.3%) of the title compound. 1H-NMR (DMSO-d6) δ 8.56 (s, 1H), 6.60 (d, J=2.7 Hz, 1H), 6.53 (d, J=8.7 Hz, 1H), 6.43 (dd, J=8.7, 2.4 Hz, 1H), 2.28 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076488B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-39205e5895124b97bbb2f1897730a49b |
| Source note | uspto-grants-2011_12 |