HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminophenol → 4-(3-Aminophenoxy)-N-methylpyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminophenol | HCID 403 | — |
| Reactant | 4-(4-Aminophenoxy)-N-methylpicolinamide | HCID 16655129 | — |
| Product | 4-(3-Aminophenoxy)-N-methylpyridine-2-carboxamide | HCID 23614557 | — |
Reaction Steps
The title compound was prepared in the same manner described for 4-(4-aminophenoxy)pyridine-2-carboxylic acid methylamide, substituting 3-aminophenol for 4-aminophenol. 1H-NMR (DMSO-d6) δ 8.75 (br q, J=4.8 Hz, 1H), 8.48 (d, J=6.3 Hz, 1H), 7.39 (d, J=2.1 Hz, 1H), 7.15 to 7.07 (m, 2H), 5.51 to 6.47 (m, 1H), 6.31 to 6.24 (m, 2H), 5.40 (s, 2H), 2.77 (d, J=5.1 Hz, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076488B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-bb768feed75a43988383ea67838c1a15 |
| Source note | uspto-grants-2011_12 |