HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminophenol → 4-(4-amino-3-methylphenoxy)-N-methylpyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminophenol | HCID 403 | — |
| Reactant | 4-(4-Aminophenoxy)-N-methylpicolinamide | HCID 16655129 | — |
| Product | 4-(4-amino-3-methylphenoxy)-N-methylpyridine-2-carboxamide | HCID 23137246 | — |
Reaction Steps
The title compound was prepared in the same manner described for 4-(4-aminophenoxy)pyridine-2-carboxylic acid methylamide, substituting 4-amino-3-methylphenol for 4-aminophenol. 1H-NMR (acetone-d6) δ 8.39 (d, J=5.7 Hz, 1H), 8.29 (br s, 1H), 7.51 (dd, J=2.7, 0.6 Hz, 1H), 6.98 (dd, J=5.7, 2.4 Hz, 1H), 6.82 (br s, 1H), 6.77 to 6.76 (m, 2H), 4.56 (br s, 2H), 2.92 (d, J=5.1 Hz, 3H), 2.16 (d, J=1.0 Hz, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076488B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-3f2fc586560b4bf9998fe734e2837a82 |
| Source note | uspto-grants-2011_12 |