HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminophenol → HCID 59987421, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminophenol | HCID 403 | — |
| Reactant | 4-Chloro-2-pyridinecarbonitrile | HCID 693342 | — |
| Reactant | 4-Chloro-N-methylpicolinamide | HCID 1476814 | — |
| Reactant | 4-(4-Aminophenoxy)-N-methylpicolinamide | HCID 16655129 | — |
| Product | HCID 59987421 | HCID 59987421 | — |
Reaction Steps
The title compound was prepared in the same manner described for 4-(4-aminophenoxy)pyridine-2-carboxylic acid methylamide, substituting 4-amino-2-methoxyphenol for 4-aminophenol, and 4-chloro-2-cyanopyridine for 4-chloropyridine-2-carboxylic acid methylamide. 1H-NMR (DMSO-d6) δ 8.50 (d, J=6.0 Hz, 1H), 7.49 (d, J=2.7 Hz, 1H), 7.00 (dd, J=5.7, 2.4 Hz, 1H), 6.82 (d, J=8.4 Hz, 1H), 6.37 (d, J=2.4 Hz, 1H), 6.16 (dd, J=8.7, 2.7 Hz, 1H), 5.25 (s, 2H), 3.62 (s, 3H); MS LC-MS (M+H)+=242.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076488B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-dc4a732d85994fb39f24312fb963d8d0 |
| Source note | uspto-grants-2011_12 |