HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-3-chlorophenol → 4-(4-Amino-2-chlorophenoxy)picolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-3-chlorophenol | HCID 87184 | — |
| Reactant | 4-(4-Amino-3-chlorophenoxy)picolinamide | HCID 23153584 | — |
| Product | 4-(4-Amino-2-chlorophenoxy)picolinamide | HCID 43517671 | — |
Reaction Steps
The title compound was prepared in the same manner described for 4-(4-amino-3-chlorophenoxy)pyridine-2-carboxamide, substituting 4-amino-2-chlorophenol for 4-amino-3-chlorophenol. 1H-NMR (DMSO-d6) 88.46 (d, J=5.7 Hz, 1H), 8.08 (s, 1H), 7.69 (s, 1H), 7.25 (d, J=2.7 Hz, 1H), 7.08 (dd, J=2.7, 5.7 Hz, 1H), 7.02 (d, J=8.4 Hz, 1H), 6.74 (d, J=2.7 Hz, 1H), 6.59 (dd, J=2.7, 8.7 Hz, 1H), 5.50 (s, 2H); MS LC-MS (MH)+=264.1, RT=1.76 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076488B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-93de2af183624a68b51e07c67589628e |
| Source note | uspto-grants-2011_12 |