HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-3-chlorophenol → 4-(4-Amino-2-chlorophenoxy)picolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-3-chlorophenol | HCID 87184 | — |
| Reactant | 4-(4-Amino-3-chlorophenoxy)picolinamide | HCID 23153584 | — |
| Product | 4-(4-Amino-2-chlorophenoxy)picolinamide | HCID 43517671 | — |
Reaction Steps
The title compound was prepared in the same manner described for 4-(4-amino-3-chloro-phenoxy)pyridine-2-carboxamide, substituting 4-aminophenol for 4-amino-3-chlorophenol. 1H-NMR (DMSO-d6) δ 8.43 (d, J=5.7 Hz, 1H), 8.07 (broad s, 1H), 7.66 (broad s, 1H), 7.31 (d, J=2.7 Hz, 1H), 7.07 (dd, J=5.7 Hz, 2.7 Hz, 1H), 6.85 (d, J=9.0 Hz, 2H), 6.62 (d, J=8.7 Hz, 2H), 5.17 (broad s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076488B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-efdb938fb5914248ac6952f9dacc0ec6 |
| Source note | uspto-grants-2011_12 |