HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-2-chlorophenol → 4-(4-Amino-3-chlorophenoxy)-n-methylpicolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-2-chlorophenol | HCID 77578 | — |
| Reactant | 4-(2-(N-methylcarbamoyl)4-pyridyloxy)-3-chloroaniline | HCID 23614562 | — |
| Product | 4-(4-Amino-3-chlorophenoxy)-n-methylpicolinamide | HCID 23614561 | — |
Reaction Steps
The title compound was prepared in the same manner described for 4-(4-amino-2-chlorophenoxy)pyridine-2-carboxylic acid methylamide, substituting 4-amino-3-chlorophenol for 4-amino-2-chlorophenol. 1H-NMR (DMSO-d6) δ 8.76 (m, 1H), 8.47 (d, 1H), 7.35 (s, 1H), 7.15 (s, 1H), 7.06 (dd, 1H), 6.85 to 6.95 (m, 2H), 5.43 (s, 2H), 2.78 (d, 3H); MS LC-MS [M+H]+=278.1 [M+H]+, RT=2.19 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076488B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-c8e83cc8f5ca4a47aa08e750dcfab9b1 |
| Source note | uspto-grants-2011_12 |