4-Nitrophenol → HCID 59987435, compound

HRID 658491Notes

Reaction equation

HRID 658491 reaction equation
[CH3:1][NH:2][C:3]([C:5]1[CH:10]=[C:9]([CH2:11][O:12][C:13]2[CH:18]=[CH:17][C:16](N)=[CH:15][CH:14]=2)[CH:8]=[CH:7][N:6]=1)=[O:4].[N+:20](C1C=CC(O)=CC=1)([O-])=O>>[CH3:1][NH:2][C:3]([C:5]1[CH:10]=[C:9]([CH2:11][O:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([NH2:20])[CH:14]=2)[CH:8]=[CH:7][N:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 9804-NitrophenolHCID 59987460HCID 59987460, compound

Product 1

HCID 59987435HCID 59987435, compound

Procedure

The title compound was prepared in the same manner described for 4-(4-aminophenoxymethyl)pyridine-2-carboxylic acid methylamide, substituting 3-nitrophenol for 4-nitrophenol. 1H-NMR (CD3OD) δ 8.40 (d, J=4.5 Hz, 1H), 7.54 (d, J=2.1 Hz, 1H), 7.13 (t, J=6.3 Hz, 1H), 7.00 (dd, J=4.2, 1.8 Hz, 1H), 6.62 to 6.59 (m, 1H), 6.43 (t, J=1.8 Hz, 1H), 6.37 to 6.34 (m, 1H), 4.89 (s, 2H), 2.93 (s, 3H).

Sources & evidence

ORD record
ord-e7f1af966cba4a30a4b009bd97b3531c
Source dataset
uspto-grants-2011_12
Patent number
US08076488B2

Reaction notes

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