Pyridine → HCID 86761477, compound

Participants

Reaction Steps

A 0° C. mixture of 1.93M solution of phosgene in toluene (8.9 mL, 17 mmol) and CH2Cl2 (80 mL) was added dropwise a solution of 5-amino-indazole-1-carboxylic acid tert-butyl ester (2 g, 8.5 mmol) and pyridine (3.5 mL, 43 mmol) in CH2Cl2 (20 mL). The reaction mixture was stirred for 1.5 h, then concentrated under reduced pressure. The residue was dissolved in CH2Cl2 (100 mL) and was used without further purification.

Provenance & Evidence