Alanine methyl ester hydrochloride → HCID 59524392, compound

HRID 658766Notes

Reaction equation

HRID 658766 reaction equation
[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH:12]=O)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].Cl.[NH2:18][C@@H:19]([CH3:24])[C:20]([O:22][CH3:23])=[O:21]>>[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12][NH:18][C@@H:19]([CH3:24])[C:20]([O:22][CH3:23])=[O:21])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 2733257Alanine methyl ester hydrochlorideHCID 112071113-(t-Butyldimethylsilyloxy)benzaldehyde

Product 1

HCID 59524392HCID 59524392, compoundYield 80%

Procedure

Prepared as in Example 12-1b from 3-(tert-butyldimethylsilyloxy)benzaldehyde (Example 12-1c) and (S)-methyl 2-aminopropanoate hydrochloride. Yield 80%, colorless liquid. MS 324 (MH+).

Sources & evidence

ORD record
ord-28cf98e5f0334e9cb1a1ba26d95f3990
Source dataset
uspto-grants-2011_12
Patent number
US08076491B2

Reaction notes

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