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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 658776Generated: October 25, 2026

Ethyl 1-aminocyclopropane-1-carboxylate hydrochloride → Ethyl 1-(3-(tert-butyldimethylsilyloxy)benzylamino)-cyclopropanecarboxylate

https://huagongshe.com/reaction/658776

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 1-aminocyclopropane-1-carboxylate hydrochlorideHCID 386203—
Reactant3-(t-Butyldimethylsilyloxy)benzaldehydeHCID 11207111—
ProductEthyl 1-(3-(tert-butyldimethylsilyloxy)benzylamino)-cyclopropanecarboxylateHCID 5952437387%

Reaction Steps

Prepared as in Example 12-1b from 3-(tert-butyldimethylsilyloxy)benzaldehyde (Example 12-1c) and ethyl 1-aminocyclopropanecarboxylate hydrochloride. Yield 87%, colorless liquid. MS 350 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076491B2
Source datasetuspto-grants-2011_12
ORD IDord-13c7b07b03504482a2d5d68005edf232
Source noteuspto-grants-2011_12