HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-Bromoethyl)benzene → HCID 53373740, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-Bromoethyl)benzene | HCID 11454 | — |
| Reactant | 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-5,5-dimethylimidazolidine-2,4-dione | HCID 59524388 | — |
| Product | HCID 53373740 | HCID 53373740 | — |
Reaction Steps
Prepared as in Example 16 from 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-5,5-dimethylimidazolidine-2,4-dione (Example 16a) and (1-bromoethyl)benzene. MS 408 (MH+). The title compound was shown to inhibit hT2R08 bitter receptor and had an IC50 of 0.15 μM.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076491B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-993cd1b453e44ecabc86b873f6b53383 |
| Source note | uspto-grants-2011_12 |