HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, (2-bromoethoxy)- → HCID 53374079, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, (2-bromoethoxy)- | HCID 68526 | — |
| Reactant | 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-5,5-dimethylimidazolidine-2,4-dione | HCID 59524388 | — |
| Product | HCID 53374079 | HCID 53374079 | — |
Reaction Steps
Prepared as in Example 12-16 from 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-5,5-dimethylimidazolidine-2,4-dione (Example 12-16a) and (2-bromoethoxy)benzene. MS 424 (MH+). The title compound was shown to inhibit hT2R08 bitter receptor and had an IC50 of 0.35 μM.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08076491B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-2e2f4691b65f4da49858a3a1de23aef1 |
| Source note | uspto-grants-2011_12 |