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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 658797Generated: October 25, 2026

3-Pyridinecarboxaldehyde → Ethyl 2-methyl-2-(pyridin-3-ylmethylamino)propanoate

https://huagongshe.com/reaction/658797

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-PyridinecarboxaldehydeHCID 10371—
ReactantEthyl 1-aminocyclopropane-1-carboxylate hydrochlorideHCID 386203—
ProductEthyl 2-methyl-2-(pyridin-3-ylmethylamino)propanoateHCID 5952439195%

Reaction Steps

Prepared as in Example 12-1b from nicotinaldehyde and ethyl 1-aminocyclopropanecarboxylate hydrochloride. Yield 95%, a white solid. MS 223 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076491B2
Source datasetuspto-grants-2011_12
ORD IDord-faa42982028645818b84c034bb81c130
Source noteuspto-grants-2011_12