Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 658804Generated: October 25, 2026

(S)-2-[4-(2-fluorobenzyloxy)benzylideneamino]propanamide → Priralfinamide

https://huagongshe.com/reaction/658804

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-[4-(2-fluorobenzyloxy)benzylideneamino]propanamideHCID 23659931—
Reactant(S)-2-((3-(2-Fluorobenzyl)-4-((2-fluorobenzyl)oxy)benzyl)amino)propanamideHCID 57745326—
ProductPriralfinamideHCID 574520793%

Reaction Steps

(S)-2-[4-(2-Fluorobenzyloxy)benzylamino]propanamide is prepared in a 93% yield from (S)-2-[4-(2-fluorobenzyloxy)benzylideneamino]propanamide by following the same procedure of Example 8, step b). The content of (S)-2-[3-(2-fluorobenzyl)-4-(2-fluorobenzyloxy)-benzylamino]propanamide is 0.02% by weight determined by HPLC (see Example 17B).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076515B2
Source datasetuspto-grants-2011_12
ORD IDord-c32c824538af4ee39ad20a6a67c33085
Source noteuspto-grants-2011_12