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HRID658847

反应详情

EQUATION

反应方程式

HRID 658847 的结构方程式

REACTANTS

反应物

2
结构：C#Cc1ccccc1
HCID10821

Phenylacetylene

C8H6

结构：CC(C)(C)OC(=O)NCCC(O)c1cccc(Br)c1
HCID57608439

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NCCC(O)c1cccc(C#Cc2ccccc2)c1
HCID66742835

未命名化合物

PROCEDURE

实验过程

Sonogashira reaction of 39 with ethynylbenzene gave tert-butyl 3-hydroxy-3-(3-(phenylethynyl)phenyl)propylcarbamate as brown oil. Yield (0.911 g, 85%): 1H NMR (400 MHz, CDCl3) δ 7.51-7.55 (m, 3H), 7.42-7.44 (m, 1H), 7.30-7.37 (m, 5H), 4.87 (bs, 1H), 4.74-4.76 (m, 1H), 3.46-3.51 (m, 1H), 3.41 (bs, 1H), 3.13-3.19 (m, 1H), 1.79-1.88 (m, 2H), 1.44 (s, 9H).