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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 658883Generated: November 2, 2026

Methyl 3-Hydroxybenzoate → HCID 18930691, compound

https://huagongshe.com/reaction/658883

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-HydroxybenzoateHCID 88068—
Reactanttert-Butyl N-(2-((methylsulfonyl)oxy)ethyl)carbamateHCID 22605302—
ProductHCID 18930691HCID 18930691—

Reaction Steps

Coupling of methyl 3-hydroxybenzoate with 2-(tert-butoxycarbonylamino)ethyl methanesulfonate following the method used in Example 9 gave methyl 3-(2-(tert-butoxycarbonylamino)ethoxy)benzoate as a light yellow oil. Yield (0.65 g, 84%): 1H NMR (400 MHz, CD3OD) δ 7.36 (t, J=8.0 Hz, 1H), 7.26 (t, J=8.0 Hz, 1H), 7.16 (ddd, J=8.4, 2.4, 0.8 Hz, 1H), 6.99 (ddd, J=8.0, 2.4, 0.8 Hz, 1H), 4.03 (t, J=5.6 Hz, 2H), 3.78 (s, 3H), 1.43 (s, 9H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076516B2
Source datasetuspto-grants-2011_12
ORD IDord-be42a10f0bda42bfbdb29b7a493a2a8c
Source noteuspto-grants-2011_12