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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 658898Generated: November 4, 2026

N-Allyl-2,2,2-trifluoroacetamide → (E)-2,2,2-trifluoro-N-(3-(3-(2-(1-hydroxycyclohexyl)ethyl)phenyl)allyl)acetamide

https://huagongshe.com/reaction/658898

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Allyl-2,2,2-trifluoroacetamideHCID 558569—
ReactantHCID 57956767HCID 57956767—
Product(E)-2,2,2-trifluoro-N-(3-(3-(2-(1-hydroxycyclohexyl)ethyl)phenyl)allyl)acetamideHCID 57956840—

Reaction Steps

Coupling of 1-(3-bromophenethyl)cyclohexanol with N-allyl-2,2,2-trifluoroacetamide following the method described in Example 118 gives (E)-2,2,2-trifluoro-N-(3-(3-(2-(1-hydroxycyclohexyl)ethyl)phenyl)allyl)acetamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08076516B2
Source datasetuspto-grants-2011_12
ORD IDord-93359cbb73994701947ea6122c0d9750
Source noteuspto-grants-2011_12