反应详情

Into a 25 ml round bottom flask was weighed 5 grams (0.0237 mole) of 4-t-butylazo-4-cyanovaleric acid and then 15 ml. of benzene and 2 ml. of thionyl chloride were added. The acid dissolved and the solution was stirred for 4 hours at 25° C. ± 2° C. (protected from the atmosphere by a CaCl2 tube). At the end of the stirring period the benzene and excess thionyl chloride were evaporated under reduced pressure leaving 5.35 grams (98.8% yield) of 4-t-butylazo-4-cyanovaleryl chloride.

1. customInto a 25 ml round bottom flask was weighed
2. dissolutionThe acid dissolved
3. customprotected from the atmosphere by a CaCl2 tube
4. customAt the end of the stirring period the benzene and excess thionyl chloride were evaporated under reduced pressure