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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 659063Generated: October 30, 2026

Dimethylformamide → Methyl 3-(cyclopentyloxy)-4-methoxy-2-(N-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)acetamido)benzoate

https://huagongshe.com/reaction/659063

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantMethyl 2-acetamido-3-(cyclopentyloxy)-4-methoxybenzoateHCID 66781936—
ProductMethyl 3-(cyclopentyloxy)-4-methoxy-2-(N-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)acetamido)benzoateHCID 66781726—

Reaction Steps

Methyl 3-(cyclopentyloxy)-4-methoxy-2-(N-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)acetamido)benzoate was prepared from methyl 2-acetamido-3-(cyclopentyloxy)-4-methoxybenzoate (Example 1, Step 4) following the procedure outlined in Example 4 (except: solvent was DMF; temp was 33° C.; time was overnight). MS (ESI): 458.2 (M+Na).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08080563B2
Source datasetuspto-grants-2011_12
ORD IDord-d02d0c8dd4124ddeb3381323838e3957
Source noteuspto-grants-2011_12