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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 659191Generated: October 25, 2026

1,2-Diaminocyclohexane, cis- → cis-N-(2-Amino-cyclohexyl)-2-cyclopropyl-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/659191

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Diaminocyclohexane, cis-HCID 342917—
Reactant2-Cyclopropyl-4-(trifluoromethyl)benzoic acidHCID 59438485—
Productcis-N-(2-Amino-cyclohexyl)-2-cyclopropyl-4-trifluoromethyl-benzamideHCID 66681224—

Reaction Steps

The title compound, yellow solid, MS: m/e=327.2 [(M+H)+], was prepared in accordance with the general method of intermediate G from cis-1,2-diaminocyclohexane and 2-cyclopropyl-4-trifluoromethyl-benzoic acid (intermediate K).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08080541B2
Source datasetuspto-grants-2011_12
ORD IDord-b9fc94ab694347f3bf2137dcf8d887dd
Source noteuspto-grants-2011_12