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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 659205Generated: October 29, 2026

2-(Trifluoromethyl)benzoic acid → 2-(Methylthio)-6-(trifluoromethyl)benzoic acid

https://huagongshe.com/reaction/659205

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzoic acidHCID 9899—
ReactantDimethyl DisulfideHCID 12232—
Reactant2-Methoxy-6-methylsulfanyl-4-trifluoromethyl-benzoic acidHCID 59197921—
Product2-(Methylthio)-6-(trifluoromethyl)benzoic acidHCID 59197903—

Reaction Steps

The title compound, white solid, MS: m/e=235.0 [(M−H)−], was prepared in accordance with the general method of intermediate A from 2-(trifluoromethyl)benzoic acid and dimethyl disulfide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08080541B2
Source datasetuspto-grants-2011_12
ORD IDord-10dc0602ae0f4508b605142c6366b15d
Source noteuspto-grants-2011_12