HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dibromopropane → cis-N-(2-Azetidin-1-yl-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dibromopropane | HCID 8001 | — |
| Reactant | cis-N-(2-Amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide | HCID 58062915 | — |
| Product | cis-N-(2-Azetidin-1-yl-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide | HCID 58062867 | — |
Reaction Steps
The title compound, light yellow solid, MS: m/e=425.2 [(M+H)+], was prepared in accordance with the general method of example 10 from cis-N-(2-amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide (intermediate H) and 1,3-dibromopropane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08080541B2 |
| Source dataset | uspto-grants-2011_12 |
| ORD ID | ord-b96f6b1548964c40bc5d9d6bd8b2dfbd |
| Source note | uspto-grants-2011_12 |