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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 659244Generated: October 25, 2026

Acetone → N-((1RS,2SR)-2-Isopropylamino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide

https://huagongshe.com/reaction/659244

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetoneHCID 180—
Reactantcis-N-(2-Amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamideHCID 58062915—
ProductN-((1RS,2SR)-2-Isopropylamino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamideHCID 76682969—

Reaction Steps

The title compound, off-white foam, MS: m/e=427.2 [(M+H)+], was prepared in accordance with the general method of example 11 from cis-N-(2-amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide (intermediate H) and acetone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08080541B2
Source datasetuspto-grants-2011_12
ORD IDord-2ae3a0823a8b493d977904e1b8656bda
Source noteuspto-grants-2011_12