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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 659246Generated: October 26, 2026

Cyclohexanone → N-((1RS,2SR)-2-Cyclohexylamino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide

https://huagongshe.com/reaction/659246

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanoneHCID 7967—
Reactantcis-N-(2-Amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamideHCID 58062915—
ProductN-((1RS,2SR)-2-Cyclohexylamino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamideHCID 76683024—

Reaction Steps

The title compound, light yellow solid, MS: m/e=467.2 [(M+H)+], was prepared in accordance with the general method of example 11 from cis-N-(2-amino-cyclohexyl)-2-methoxy-4,6-bis-trifluoromethyl-benzamide (intermediate H) and cyclohexanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08080541B2
Source datasetuspto-grants-2011_12
ORD IDord-8b564e410d5b4c23b2b1c4139a3a6947
Source noteuspto-grants-2011_12